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I Know This Much is True Trivia

Brain Snacks: Tasty Tidbits of Knowledge

While you won't find the Wequonnoc tribe anywhere (and not because the last of the Wequonnoc went the way of the Mohicans, but because they're fiction), the story of the Wequonnoc tribe mimics that of another, real, Native American tribe in Connecticut: the Mohegan. They have their own casino too, Mohegan Sun, which Lamb mirrors with the Wequonnoc Moon casino in the book.
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Thayer Kitchen, whom Dominick mentions "did drywall," is a major character in Lamb's previous book, She's Come Undone. Good to see he's still employed even after the end of that book. We haven't seen the last of Dominick either—he appears in Lamb's third book, The Hour I First Believed.
(Source.)

Dominick and Thomas didn't start out as identical twins… Lamb decided they were twins—and that Thomas was schizophrenic—about four months into writing the novel.
(Source.)